Stats for mythic rank, last 7 days — third-party aggregation, not an official Moonton figure.
Written by EllieAnth — playing MLBB since 2017 (9+ years), peak rank Mythical Immortal, 1126 stars.
A breakdown of the 10 matchups that decide Vexana games — why each one leans the way it does, what it costs you in lane, and how to play it.
Overview
What decides Vexana's matchups
Vexana dictates her matchups by forcing enemies into tightly packed teamfights where her crowd control and wave-clear excel. Landing Deathly Grasp locks down target heroes with terror, setting up an immediate burst from Cursed Blast while setting off chain-reaction explosions across minions and heroes via Nether Touch. Her ultimate, Eternal Guard, adds an airborne knockup and continuous area-of-effect damage scaling with enemy maximum health, making her devastating against clustered opponents. However, opponents exploit her complete lack of mobility and low durability; if an agile enemy dodges Deathly Grasp, Vexana becomes entirely vulnerable during Cursed Blast's 0.8-second delay.
Hard counters 2
These heroes have a structural edge over you: their kit directly shuts down the tools you rely on. Winning the lane outright is rarely the plan — the goal is to limit mistakes, give up as little tempo as possible, and look for value somewhere else on the map.
Lancelot counters Vexana because his invincibility frames completely negate her slow, skillshot-reliant crowd control and area burst. Vexana depends on landing Deathly Grasp to terrify threats and Eternal Guard to knock them airborne, setting up Cursed Blast. However, Lancelot can time Thorned Rose or Phantom Execution to become entirely untargetable and immune to damage right as her projectiles or ground delays detonate. Furthermore, Lancelot uses Puncture to dart through minions, easily dodging Cursed Blast's 0.8s delay while stacking Soul Cutter, forcing Vexana to spend her defensive crowd control on invulnerable frames.
Lane impact
During the laning phase, Vexana's intent to push Mid Lane with Cursed Blast leaves her extremely vulnerable to Lancelot's ganks from the jungle. If she casts Cursed Blast on the wave, Lancelot uses Puncture on those same minions to gain free dashes, rapidly closing the distance to her. Without Deathly Grasp available or if timed poorly into his Thorned Rose, Vexana has no escape mechanism. This forces Vexana to freeze waves near her turret, sacrificing fast lane clears, which cedes Mid Lane priority, vision control, and early rotations toward the Turtle.
How to play it
To survive against Lancelot, Vexana must play reactively and strictly track Lancelot's invincibility windows before committing her spells. Never throw Deathly Grasp while Lancelot is actively mid-animation with Thorned Rose; wait out his untargetable duration and cast it right as he re-emerges. Hold Eternal Guard for after he burns both Thorned Rose and Phantom Execution, or drop it on yourself if he dives under your turret. If Lancelot retains mobility, focus Cursed Blast on clearing waves under tower safety, shifting your win condition toward triggering Nether Touch chain explosions in teamfights.
Kadita structurally counters Vexana by invalidating her only defensive tool. When Vexana attempts to interrupt an engage using Deathly Grasp, Kadita riding inside Ocean Ode gains Control Immunity and fifty percent damage reduction, completely ignoring the fear effect while closing the gap. Furthermore, Kadita becoming untargetable during Rough Waves seamlessly dodges the delayed impact of Cursed Blast and the airborne knockup from Eternal Guard. Meanwhile, Thalassophobia regularly heals back Vexana's poke damage, forcing Vexana to spend high mana costs without securing favorable health trades.
Lane impact
Vexana holds the early wave-clearing advantage by triggering Nether Touch with Cursed Blast, pushing minion waves quickly into the enemy tower. However, extending past the Mid Lane center line opens a lethal window for Kadita. The moment Kadita unlocks Rough Waves, she can ride Ocean Ode straight through Deathly Grasp, seamlessly chaining Breath of the Ocean for a 1.5-second airborne state that leads to an instant kill. Consequently, Vexana must surrender river vision and objective setup, delaying her own rotations toward side lanes and the Turtle.
How to play it
Never throw Deathly Grasp defensively while Kadita holds Ocean Ode, as her Control Immunity will completely neutralize the projectile. Instead, clear minion waves exclusively with Cursed Blast from maximum range and immediately retreat to safety. Track the thirty-second cooldown of Thalassophobia to avoid wasting mana on shielded health pools. When team fights break out near objectives, delay summoning Eternal Guard until after Kadita commits Rough Waves, ensuring her untargetable state ends so your summoned guard can land its knockup and ongoing damage.
Unfavorable 3
You are behind in this matchup but not helpless. These opponents punish specific mistakes rather than dominating every exchange, so precise cooldown tracking and patient trading keep you in the game.
Nana's kit structurally counters Vexana's all-in burst win condition through Molina's Gift. When Vexana commits her high-cooldown Eternal Guard alongside Deathly Grasp and Cursed Blast to execute a full combo, Molina's Gift absorbs the fatal blow, rendering Nana untargetable and robbing Vexana of both the kill and her Nether Touch chain explosion passive. Furthermore, Molina Smooch serves as a defensive zone control that interrupts Vexana whenever she steps up to cast Cursed Blast, forcing Vexana to burn mana and major cooldowns without securing eliminations.
Lane impact
In Mid Lane, Vexana holds superior raw wave clear by combining Cursed Blast with Nether Touch, forcing Nana's Magic Boomerang onto defense. However, trading directly with Nana is inefficient; Molina Smooch punishes aggressive Deathly Grasp angles by transforming Vexana and stripping her Magic Defense. If Vexana overcommits Eternal Guard before popping Molina's Gift, Nana survives, reset-heals, and counters with Molina Blitz during Vexana's long downtime. Consequently, Vexana achieves early lane priority through wave pushes, but suffers high risk during prolonged trades.
How to play it
Vexana must adapt by treating Molina's Gift as an essential cooldown to track before spending Eternal Guard. Use Cursed Blast exclusively on minion waves to maintain lane priority rather than poking Nana into her passive. Avoid walking into Molina Smooch zone control; instead, bait out Magic Boomerang before using Deathly Grasp from fog of war. If Nana retains her passive, stop committing ultimate execution combos in Mid Lane. Instead, clear the wave instantly with Nether Touch explosions and rotate to assist side lanes or secure the Turtle.
Zetian holds a structural advantage over Vexana due to superior mobility and global influence. The movement speed boost from Zetian's Phoenix Strike allows her to effortlessly step out of the 0.8s delay on Cursed Blast, stripping Vexana of unassisted burst damage. When Vexana attempts to initiate with Deathly Grasp, Zetian's passive Celestial Armament provides a knockback shield that dampens close-range follow-ups. Furthermore, Fury of the Phoenix grants global vision and a map-wide stun, interrupting Vexana's setup and canceling her ambush attempts before Eternal Guard can land.
Lane impact
In the Mid Lane, Zetian dictates the tempo by casting Phoenix Strike while moving freely, shoving waves without standing still. Vexana is forced to burn mana using Cursed Blast on minions rather than trading, relying on Nether Touch explosions to keep pace. If Vexana takes a bad trade, Zetian's Phoenix Descent shreds her magic defense, placing Vexana in lethal range. As rotations begin, Zetian impacts side-lane fights instantly with Fury of the Phoenix, whereas Vexana must physically walk to fights to deliver Eternal Guard.
How to play it
To survive this lane, Vexana must prioritize wave management over direct trading. Aim Cursed Blast exclusively at minion waves to maximize Nether Touch chain explosions and clear safely from distance. Track the long cooldown of Zetian's Celestial Armament before attempting all-in playmaking, and never cast Deathly Grasp raw against a moving Zetian using Phoenix Strike. Instead, save Eternal Guard for teamfights around major objectives, dropping the summoned knight directly on Zetian to disrupt her channeling and force her out of Phoenix Descent range.
Valir counteracts Vexana's primary initiation pattern through Vengeance Flame, which instantly cleanses the terror status from Deathly Grasp or the knockup from Eternal Guard. Furthermore, Searing Torrent creates distance, repelling Eternal Guard and preventing Vexana from maintaining area control. Because Vexana relies on hitting Deathly Grasp to guarantee Cursed Blast's 0.8-second delayed damage, Valir's ability to purify her initial crowd control and disengage strips Vexana of her high-burst combo, forcing her to burn her long ultimate cooldown while Valir retains trade dominance with continuous Burst Fireball charges.
Lane impact
In the Mid Lane, Vexana maintains a distinct advantage in wave clear speed. A single Cursed Blast combined with Nether Touch detonations rapidly clears minion waves, whereas Valir relies on Burst Fireball, which only refunds charges when hitting enemy heroes rather than minions. However, if Vexana steps forward to trade, Valir's Burst Fireball slows her, enabling continuous Ashing stacks that lead to a stun. Vexana must use her rapid wave clear to immediately break line of sight, rotating to side lanes rather than posturing for Mid Lane trades against his superior zoning.
How to play it
Never initiate on Valir with Deathly Grasp while his Vengeance Flame is available; track his ultimate cooldown rigorously and hold your crowd control until after he burns it or is forced to cleanse another threat. Rely on Cursed Blast strictly for wave clearing from absolute maximum range. During skirmishes, summon Eternal Guard behind Valir or onto his allies rather than directly in front of him to prevent Searing Torrent from knocking it completely out of the fight. Your winning path relies on fast shove-and-rotate cycles, securing side-lane advantages instead of direct duels.
Favorable 4
Your kit has the edge here. These are the matchups where you should look to build a lead early and convert it, rather than playing for scaling.
Vexana holds the advantage because her superior range and waveclear outpace Eudora's short-range burst window. Cursed Blast coupled with Nether Touch allows Vexana to erase minion waves instantly from safety, forcing Eudora to spend mana and Forked Lightning on clearing rather than trading. Eudora requires close proximity to land Ball Lightning and trigger her Superconductor passive into Thunder's Wrath. Vexana negates this approach by deploying Eternal Guard from afar to airborne Eudora, or throwing Deathly Grasp to terrify her before she gets within point-and-click range.
Lane impact
In the Mid Lane, Vexana commands constant wave priority. A quick Cursed Blast triggers Nether Touch explosions across the wave, forcing Eudora under her tower where she wastes Ball Lightning and Forked Lightning to last-hit. This wave control lets Vexana rotate first to side lanes or secure early Turtle setups. Eudora is restricted to hiding in unlit bushes, but Vexana can safely check brushes using Deathly Grasp or summon Eternal Guard to grant vision and disrupt potential bush ambushes without risking her fragile health pool.
How to play it
Maintain maximum distance and never walk blindly into unrevealed bushes where Eudora can lead with Ball Lightning. Clear incoming waves immediately using Cursed Blast, then immediately retreat toward your team or look for rotations. When contesting objectives, lead with Eternal Guard to knock Eudora airborne and force out her Thunder's Wrath on the summoned minion rather than yourself. If Eudora moves forward aggressively, throw Deathly Grasp along her path to terrify her, breaking her combo before she can apply Superconductor.
Odette relies entirely on channeling Swan Song during team fights to deal massive area damage while relying on her temporary shield for protection. Vexana completely counters this power spike because both Deathly Grasp and Eternal Guard inflict high-level crowd control capable of breaking channelled abilities instantly. Summoning Eternal Guard knocks Odette airborne for 0.8 seconds, immediately shutting down Swan Song before it delivers its sustained damage output. Forced to cancel her ultimate early, Odette loses her primary defensive buffer and main offensive threat, rendering her reliant on Blue Nova and Avian Authority while completely exposed.
Lane impact
During the laning phase in Mid Lane, Vexana clears minion waves rapidly by pairing Cursed Blast with her Nether Touch passive explosions. This forces Odette to spend Blue Nova and Avian Authority defensively just to push back the wave, preventing her from leveraging Lakeshore Ambience bounces against Vexana. Because Odette cannot channel Swan Song safely once Vexana hits level four, Vexana gains full authority over Mid Lane wave management. Vexana uses this constant wave priority to roam early, securing vision and securing objectives like the Turtle while Odette is pinned under tower.
How to play it
As Vexana, never open an engagement with Eternal Guard or Deathly Grasp if Odette still holds Swan Song. Instead, clear minion waves using Cursed Blast and force Odette to commit her dash or ultimate first. The moment Odette initiates Swan Song, instantly cast Eternal Guard directly onto her position to knock her airborne and terminate the channel. If Eternal Guard is unavailable, landing Deathly Grasp provides the terrify effect needed to interrupt her cast. Once her ultimate is canceled, collapse alongside your summoned knight to burst her down before Blue Nova resets.
Gord relies heavily on stationary channeling during Mystic Gush to output his primary damage, which makes him extremely vulnerable to Vexana. Either Deathly Grasp or the knockback from Eternal Guard immediately cancels his beam while leaving him defenseless. While Gord can stack Mystic Favor rapidly through Mystic Injunction, his absolute lack of mobility prevents him from dodging Cursed Blast. Vexana forces Gord to trade his position and major cooldowns first, consistently invalidating his primary kill condition with her reliable crowd control.
Lane impact
In the Mid Lane, Gord uses Mystic Injunction for rapid wave clearing, but Vexana matches his push effortlessly by triggering Nether Touch chain explosions with Cursed Blast. The danger for Gord intensifies once both heroes reach level four. Because Gord must stay motionless to optimize Mystic Gush, he loses the freedom to secure lane priority or dictate team fights around the Turtle. Vexana can lock down the lane, denying Gord favorable rotation windows while forcing him to play passively behind his minions.
How to play it
Hold Deathly Grasp specifically as a counter to Gord's actions rather than throwing it out on cooldown. Sidestep his bouncing Mystic Projectile, and the instant Gord begins channeling Mystic Gush, throw Deathly Grasp straight down his beam line to interrupt him. Follow up immediately by dropping Eternal Guard onto his immobile frame for an airborne knockup, securing a guaranteed Cursed Blast strike. If Gord hesitates to cast his ultimate, initiate from the bushes with Eternal Guard to burst his low-durability kit before he can respond.
Vexana holds a structural advantage over Alice due to severe range disparities and counter-engage tools. Alice relies on Flowing Blood to bridge the gap and activate Blood Ode alongside Blood Awe. However, Vexana can effortlessly track the trajectory of Flowing Blood and pre-cast Deathly Grasp at Alice's arrival location. The guaranteed terrify interrupts Alice's dive, allowing Vexana to immediately drop Cursed Blast and summon Eternal Guard to knock Alice airborne before she can sustain off hero hits or reduce her cooldowns.
Lane impact
From level one, Vexana out-shoves Alice with minimal effort. Combining Cursed Blast with passive Nether Touch explosions wipes Mid Lane minion waves instantly, while Alice is forced to consume heavy mana using Flowing Blood just to manage her wave. This wave control grants Vexana constant priority to secure map control and contest the Turtle early. If Alice tries to trade by teleporting forward, she takes severe damage from lingering minion explosions and Vexana's range, ensuring Alice remains pinned under her tower throughout the early game.
How to play it
Never throw Deathly Grasp randomly into the lane; hold it specifically as a reaction to Alice's Flowing Blood. The instant Alice recast teleports her to the sphere, hit her with Deathly Grasp to apply terrify, then layer Cursed Blast and Eternal Guard directly on top of her. Keep your distance so Alice cannot immobilize you with Blood Awe or drain you with Blood Ode. Let Eternal Guard's percentage Max HP attacks chip her down while you safely maintain distance from her sustained damage area.
Best allies 1
Heroes whose kit compounds with yours. Drafting alongside them turns your individual strengths into a coordinated threat.
Tigreal solves Vexana's core weakness—her delayed damage—by clumping enemies together with Implosion or pushing them into tight corridors via Sacred Hammer. When Tigreal pulls multiple targets into a single spot, Vexana can effortlessly land Cursed Blast without fearing enemies walking out of its zero point eight second delay. Furthermore, dropping Eternal Guard into Tigreal's channel adds an airborne knockup atop his stun, ensuring all trapped targets inherit Nether Curse. When one victim perishes, the resulting explosions from Nether Touch ripple through the tightly grouped crowd, multiplying their collective area damage exponentially.
Lane impact
Together in the Mid Lane, this duo controls choke points near the Turtle and Lord pits with unmatched dominance. Tigreal clears vision by scouting bushes, using Attack Wave to slow approaching roamers while Vexana rapidly wipes minion waves using Cursed Blast. During river skirmishes, Tigreal initiates by charging out of the river brush with Sacred Hammer to shove defenders directly toward Vexana. This displacement guarantees Vexana can follow up with Deathly Grasp to chain terrify effects, effectively locking down enemy Junglers and preventing contested objective takes before neutral fights even begin.
How to play it
Execution relies entirely on patient spell sequencing. Vexana must hold Cursed Blast and Eternal Guard until Tigreal commits with Implosion or the second activation of Sacred Hammer. Prematurely casting Cursed Blast onto moving targets wastes her main damage source. Once Tigreal pulls enemies together, Vexana should instantly drop Eternal Guard to layer the airborne crowd control, followed immediately by Cursed Blast under their feet. To secure fleeing survivors after the initial burst, fire Deathly Grasp to inflict terrify, allowing the summoned Eternal Guard unit to finish them off with heavy basic attacks.
Matchup relationships for 3 of these pairings come from the game's own hero data; the rest are selected from the heroes you actually meet in this lane. All written analysis is AI-generated from both heroes' ability kits and reviewed automatically for accuracy — it describes kit interactions, not live win rates.
